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RNA Editing and Its Potential to Improve Rett Syndrome Symptoms

RNA editing, one of six genetic-based strategies that RSRT is pursuing for Rett syndrome, has seen explosive growth in the last handful of years and has generated attention from many academic labs and companies – and with good reason. A paper published in August 2022 online in Proceedings of the National Academy of Sciences shows that RNA editing can improve symptoms in a mouse model of Rett syndrome.

On August 25, 2022, the authors of that paper, Gail Mandel, PhD, and John Sinnamon, PhD, joined RSRT CEO Monica Coenraads for a discussion about what this discovery means for our progress toward a Rett syndrome cure. Having received funding from RSRT for more than a decade, the Mandel lab at Oregon Health and Science University has put RNA editing on the map for Rett.

Recording

More Resources

Our Plan for a Cure: RNA Editing

VIDEO: Explain It To Me! RNA Editing

Rett News Articles About RNA Editing