The stakes are high. Our efforts aim higher.

RSRT was launched in 2008 to drive research toward a cure for Rett Syndrome and related MECP2 disorders. Our mission is urgent: 15,000 girls and women in the United States and 350,000 globally live with the agonizing symptoms of Rett Syndrome.

RSRT funds more research than any other Rett organization in the U.S. and abroad. Since 2008, RSRT has awarded $44 million to research. An average of ninety-six percent of every dollar donated to RSRT goes directly to our research program. Keeping our internal team lean and fiercely motivated allows us to focus funds and energy on what matters most: healing our children as quickly as possible.

As one of the few neurological disorders to show dramatic symptom reversal in mice, Rett Syndrome has attracted unprecedented interest from university and pharmaceutical scientists. Through innovative research and constant engagement with scientists, clinicians, industry, investors and affected families, RSRT is at the epicenter of this activity.

We do more than just write checks: we are changing the landscape of Rett research. We set the research agenda by proactively identifying and monitoring promising therapeutic areas, seeking out scientific and industry partnerships and working closely with them to advance programs through the drug development pipeline. We are risk takers who do not shy away from bold and innovative projects unlikely to be funded by the NIH or other more conventional funding agencies.

We believe Rett Syndrome can be cured, but time matters. A rigorous, coordinated, and agile research agenda will get us there as quickly as possible. Our ultimate goal is to become obsolete – by finding a cure.

Key facts about RSRT

More information about who we are, what we do and how we do it.

Our Values

Objectivity

Falling in love with the science we fund is dangerous.

Transparency

Accountability for every dollar donated and its impact on research.

Truth, Not Hype

Showing honest results, no sugar coating or redundant hype.

Time Matters

Urgency is an understatement, we fight every single day.

Our People

Rett history: an interactive timeline

Our Alliances

Annual Report

2016