Gail Mandel, Ph.D.

Senior Scientist, Vollum Institute Investigator, Howard Hughes Medical Institute

Dr. Mandel is a Senior Scientist in the Vollum Institute at the Oregon Health & Science University and a Howard Hughes Medical Institute Investigator. She has been on the faculty of Harvard Medical School, Tufts University, and SUNY at Stony Brook and has received numerous awards for her outstanding contributions to molecular neuroscience.

Her research is focused on revealing molecular mechanisms responsible for regulation of gene expression and excitability in the nervous system.The Mandel lab was the first to discover a transcription factor called REST, a master controller of excitability genes expressed only in the nervous system. REST is also expressed in non-neuronal cells where it functions as a tumor suppressor.

During her distinguished career, Mandel has won a number of awards, including appointment as fellow of the American Association for the Advancement of Science, Jacob J. Javits Neuroscience Investigator Award, and McKnight Investigator Award in Neurosciences. She is a member of the National Academy of Sciences.

Dr, Mandel did her undergraduate and graduate work at UCLA and a postdoctoral fellowship at the University of California, San Diego.

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