Michael E. Greenberg, Ph.D.

Chair, Department of Neurobiology, Harvard Medical School

The Greenberg lab focuses on identifying mechanisms which trigger proliferation, differentiation and survival of neurons during development, and adaptive responses in the mature nervous system. Professor Greenberg is Chair of the Department of Neurobiology at Harvard University. He currently serves on the editorial boards of Neuron; Journal of Neuroscience, Learning & Memory; Molecular & Cellular Neuroscience. He is the recipient of numerous honors and awards, including the McKnight Innovation in Neuroscience Award and the Edward M. Scolnick Prize in Neuroscience (McGovern Institute).

Research in the Greenberg laboratory has focused on the identification of a genetic program that is activated by neuronal activity, the mechanisms of signal transduction that carry the neuronal activity-dependent signal from the membrane to the nucleus, and the identification of regulators of this experience-dependent process that affect synapse development and plasticity. Professor Greenberg is particularly interested in those activity-dependent processes whose dysfunction can lead to the development of diseases of cognitive function.

One of his current projects is to characterize the mechanisms that control the activity-induced transcription of the gene that encodes Brain-Derived Neurotrophic Factor (BDNF), of particular interest in Rett Syndrome.

Professor Greenberg is a fellow of the American Academy of Arts and Sciences and the National Academy of Science. He received his PhD from Rockefeller University.

Our People